Herbal Treatment of Scorpion Envenomation: Plant Extracts Inhibited Opisthacanthus Capensis Venom Phospholipase A2 Activity
نویسندگان
چکیده
منابع مشابه
Effectiveness of anti scorpion venom for red scorpion envenomation.
OBJECTIVE To study the efficacy of anti-scorpion venom plus prazocin. METHODS Comparison of clinical features, outcome and duration of stay between children receiving anti-scorpion venom plus prazocin or prazocin alone for management of red scorpion envenomation. RESULTS Requirement for dopamine and requirement and duration of dobutamine therapy were significantly less in patients received ...
متن کاملOcyKTx2, a new K+-channel toxin characterized from the venom of the scorpion Opisthacanthus cayaporum
Opisthacanthus cayaporum belongs to the Liochelidae family, and the scorpions from this genus occur in southern Africa, Central America and South America and, therefore, can be considered a true Gondwana heritage. In this communication, the isolation, primary structure characterization, and K⁺-channel blocking activity of new peptide from this scorpion venom are reported. OcyKTx2 is a 34 amino ...
متن کاملDiagnosis of snake envenomation using a simple phospholipase A2 assay
Diagnosis of snake envenomation is challenging but critical for deciding on antivenom use. Phospholipase A2 enzymes occur commonly in snake venoms and we hypothesized that phospholipase activity detected in human blood post-bite may be indicative of envenomation. Using a simple assay, potentially a bedside test, we detected high phospholipase activity in sera of patients with viper and elapid e...
متن کاملAssaying phospholipase A2 activity.
Mammalian cells contain many structurally and functionally diverse phospholipases A2 (PLA2) that catalyze the hydrolysis of sn-2 fatty acid from membrane phospholipid. Assays are described for measuring the activity of Group IVA cytosolic PLA2alpha(cPLAalpha) and for secreted PLA2s (sPLA2) that are suitable for purified enzymes and for measuring activity in crude cell lysates and culture medium...
متن کاملUnusual presentations of scorpion envenomation.
Scorpions are nocturnal arthropods that inject their venom through the victims' skin by stingers. By the envenomation, clinical manifestations in a wide spectrum may occur, including pain at one side and death because of severe cardiopulmonary or neurological abnormalities. Sometimes the victim cannot describe the insect or does not remember even being stung after the event. We present two case...
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ژورنال
عنوان ژورنال: Advances in Biochemistry
سال: 2014
ISSN: 2329-0870
DOI: 10.11648/j.ab.20140204.12